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Patients should discuss treatment duration expectations with their prescriber
Metformin primarily reduces hepatic glucose production, while GLP-1RAs enhance insulin secretion in response to meals 20,21,22

2013;369:145-154) found that intensive lifestyle intervention focused on weight loss did not reduce cardiovascular events in a large cohort of adults with overweight/obesity and type 2 diabetes

Indian J Endocrinol Metab 2013;17:413421 [DOI] [PMC free article] [PubMed] [Google Scholar] 13.Byetta (exenatide) prescribing information

When blood sugar is high, GIP has minimal effect on glucagon
