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CBO projects that legislation repealing the prohibition would increase drug spending by $38 billion, with offsetting health savings of $3 billion, over the 2026-2034 period

In clinical trials of FDA-approved semaglutide and tirzepatide, participants using medication plus lifestyle changes lost more weight than placebo groups

Lancet Neurol (2020) 19:1112

Seven additional trials will report throughout 2026

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