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Another meta-analysis conducted on adolescents with overweight/obesity without T2D reported that GLP-1RAs had a better anti-obesity effect when compared to placebo or lifestyle modification (semaglutide is better than liraglutide and exenatide for weight control) [35]

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The JAMA Network Open Study Study Design Database: TriNetX, which contains records from millions of U.S

Code availability The published article includes all data generated or analyzed during this study

These potent systemic actions lead to a reduction in visceral adiposity and dramatically improve systemic metabolic control ( These systemic improvements translate directly to the liver, where GLP-1 RAs provide potent hepatic benefits that extend beyond simple weight loss (Summary of studies evaluating the role of GLP-1RAs in SLDs presented in Table 1)