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Monitor Bone Health : If you take omeprazole long-term, consider supplements or dietary sources of calcium and vitamin D to support bone health

Monotherapy Use of Semaglutide in Patients with Type 2 Diabetes Mellitus In a 30-week double-blind trial (NCT02054897), 388 patients with type 2 diabetes mellitus inadequately controlled with diet and exercise were randomized to Semaglutide 0.5 mg or Semaglutide 1 mg once weekly or placebo

Both drugs have a black box warning, the most serious warning required by the FDA

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1.4 How much weight can you lose on semaglutide Semaglutide can lead to significant average weight loss over 68 weeks, with clinical trials indicating an average reduction of approximately 15% to 16% of body weight