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In addition, GLP-1- exerts neuroprotective as well as cardioprotective role by reducing inflammation, stimulating nerve growth and affecting lipid metabolism (11, 13)

Liraglutide (Victoza / Saxenda) Liraglutide was one of the earlier GLP-1 receptor agonists to reach the market, approved first for diabetes and later for weight loss under the brand name Saxenda

Curr Diabetes Rev 19:3145 Gejl M, Gjedde A, Egefjord L et al (2016) In Alzheimers disease, 6-month treatment with GLP-1 analog prevents decline of brain glucose metabolism: randomized, placebo-controlled, double-blind clinical trial

13 The first four trials were designed primarily to assess cardiovascular safety in patients with T2D and yielded unexpected beneficial results

The lower intestine produces potent amounts of natural GLP after a meal