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While this initial weight loss is encouraging, the most significant benefits typically appear after 3-6 months on maintenance doses

Additionally, rapid weight loss may temporarily reduce the cushioning and support muscles provide to the spine

During your first week, you may experience mild side effects, such as nausea or gastrointestinal discomfort

[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Leoni M.L.G., Mercieri M., Viswanath O., Cascella M., Rekatsina M., Pasqualucci A., Caruso A., Varrassi G
You should see a doctor if: The pain is severe or doesnt improve with rest and over-the-counter medications
