when were glp 1 drugs approved GLP-1 use peaks in middle age, then drops at 65 Lilly is now pharma's top

These are used as treatment options for type 2 diabetes by helping to control blood sugar levels

Recent post mortem studies revealed that GLP-1R expression was downregulated in the dorsal lateral prefrontal cortex and hippocampus of patients suffering from mood disorders, and those changes further correlated with an elevated body mass index (BMI) [79]

This is due to a combination of fear of self-injection, even with an auto-injection device, as well as the stigma many living with diabetes have that moving to injections means they have failed. Managing expectations for results : Patients may stop treatment if they dont see immediate weight loss results, whether based on expectations of rate or extent of weight loss

I saw folks discussing when to take GLP1, so a large number of people said to take it at night

Heres what they do: Help your body release insulin when your blood sugar is high Reduce another hormone called glucagon that usually increases blood sugar Slow down digestion , so you feel full for longer Send signals to your brain to curb hunger and reduce cravings This multi-action approach is what makes GLP-1 drugs helpful in both type 2 diabetes and weight management If Our Body Already Makes GLP-1, Why Take It From Outside