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Owing to these effects, liraglutide, a GLP-1 analog, has been studied as a potential drug for the treatment of pre-eclampsia, a pregnancy specific disorder, defined as new-onset hypertension after 20th week of gestation accompanied by proteinuria, as it is found to have anti-inflammatory and antioxidative effects ( Placental ischemia, as the causative factor for preeclampsia, leads to dysfunction of maternal vascular endothelium causing reduced synthesis of vasodilators and increased synthesis of endothelin, a potent vasoconstrictor

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[DOI] [PMC free article] [PubMed] [Google Scholar] 115.Song N, Xu H, Liu J, Zhao Q, Chen H, Yan Z, et al

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Weight Loss One study found that after one year, participants with type 1 diabetes who took an SGLT-2 inhibitor had an average weight loss of 4.4 percent