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Clinical trials are often limited in the size and diversity of patients able to participate

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[1] Diagnosis [1] [2] Accurate diagnosis typically requires a strong level of clinical suspicion

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Combination pharmacotherapy is generally off-label and requires specialist oversight

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Its possible to see weight loss in the first month of treatment

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Finally, no long-term projections of short-term data are required, avoiding the uncertainty associated with data extrapolation

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