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in this context, preventing the activation of DNA repair pathways in cancer cells would contribute to a therapeutic effect (Lee et al., 2011)
Boxed warning class effect: contraindicated in clients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
For GLP-1 drugs, this is particularly important
If you need urgent advice when your GP surgery is closed, contact NHS 111 (online at 111.nhs.uk or by telephone)
Phase 2: Cagrilintide introduction (weeks 9-16) Once retatrutide at 2 mg is well-tolerated, introduce cagrilintide at the lowest dose
