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The key findings provide the most reliable timeline for expected results: Week 4: Average weight loss of approximately 1 to 2% of body weight Week 12: Average weight loss of approximately 5 to 6% of body weight Week 20: Average weight loss of approximately 10% of body weight Week 40: Average weight loss of approximately 13 to 14% of body weight Week 68: Average weight loss of approximately 15 to 17% of body weight These are averages, meaning some participants lost more and some lost less

The most common side effects (incidence 5%) may include: nausea, diarrhea, vomiting, constipation, stomach-area pain, headache, tiredness (fatigue), heartburn, dizziness, feeling bloated, belching, low blood sugar in patients with type 2 diabetes, gas, stomach infection (gastroenteritis), acid reflux disease, and common cold symptoms

Were calling for change, which means putting the health of Americans first through affordable and available care. Still, the conversation has become less about legacy pharmaceutical firms versus industry newcomers and more about patient safety

doi: 10.1056/NEJMoa0804381

All three share similar gastrointestinal side effect profiles: nausea, diarrhea, constipation, and abdominal discomfort
