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Additionally, these medications enhance glucose-dependent insulin secretion from pancreatic beta cells whilst suppressing inappropriate glucagon release, thereby improving glycaemic control in individuals with type 2 diabetes

Clinicians began exploring this approach for a few reasons: Not everyone needs aggressive appetite suppression to improve metabolic health Some people are more sensitive to GLP-1 medications Side effects often increase with higher doses Cost and long-term sustainability matter Women, in particular, started asking different questions

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