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Gradual dose reduction may help stabilize appetite signals during the transition
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doi:10.1038/s41366-025-01943-x
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A notable study, the BRAVES trial, demonstrated histological improvement in MASH without worsening of fibrosis in 55 % of patients undergoing Roux-en-Y gastric bypass or sleeve gastrectomy after one year, compared to only 15 % in patients who undertook lifestyle modification alone [202]
