glp-1 medullary thyroid cancer receptors (GLP-1R) are expressed in premalignant lesions in human Letter: Association Between Incretin Mimetics

Furthermore, the study showed that AP GLP-1R neurons were not required for reducing food intake, while NTS GLP-1R neurons could evoke satiation without aversive effects, highlighting future directions for a non-aversive GLP-1R drug [74] (Fig

Tirzepatide may be suitable for adults who are classified as obese, with a body mass index (BMI) of 30 or higher, or those who are overweight with a BMI of 27 or higher and have related health conditions such as hypertension, type 2 diabetes, or dyslipidemia

This resource is designed for practitioners working with clients on GLP-1 medications

Am J Physiol Renal Physiol (2011) 301(2):F35563

It appears that only in RYGB and SG patients intestinal derived GLP-1 has a true endocrine role, while in healthy individuals, localized, paracrine and neuronal signals primarily define the GLP-1 physiology