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The GLP-1 stimulating effect is the most novel aspect of its inclusion in Activate, but again, dose is everything

The most common adverse effect of SGLT2i is genital mycotic infections (GMIs)

For many, this means dramatic weight loss often 1520% of body weight as well as improved blood sugar control

Cognitive Functioning/Dementia At least 5 studies (1 case-control, 1 cohort, 3 RCTs) discussed the role of GLP-1 agonists and their action in AD and dementia

Still, more research is needed on GLP-1s and testosterone to fully understand the effects, says Michael Wierschem, MD, urologist and founder of Dallas Men's Health