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Your genetic predisposition to gastrointestinal sensitivity can influence whether you experience heartburn on GLP-1 therapy

A 2025 perspective proposed that GLP-1s could influence epigenetic pathways involved in fibrosis and hepatocellular carcinoma risk in the aging liver [6]

Long-term outcomes after bariatric surgery: a systematic review and meta-analysis of weight loss at 10 or more years for all bariatric procedures and a single-centre review of 20-year outcomes after adjustable gastric banding

Cell Metab 6 : 1324

There was also a trend towards a significant reduction in IL-6 in GE2, compared to vehicle treated, but only on the SD diet ( p = 0.054, Cohens d =0.876
