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Nevertheless, a number of other hypotheses have been suggested and both GIP receptor activation and GIP receptor antagonism have been proposed as potential mechanisms to tirzepatides efficacy [53]

2013c;38(8):125970

2024;11:e146625

Genetic evidence that diabetes drug GLP-1 receptor agonists achieve weight loss primarily by reducing fat mass more than muscle
Real-world evidence (RWE) was a major contributor in uncovering some of these unexpected benefits
