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Dig Dis Sci 2003

Because of this, it is called a triple agonist

Gastroparesis is a medical condition that affects the normal movement of the muscles in the stomach, leading to delayed emptying of food from the stomach into the small intestine

This is called lean mass loss, and it's the one outcome that turns successful weight loss into a longer-term problem slowing metabolism, reducing strength, and making weight maintenance harder once you stop or reduce the medication

Patients lost weight continuously throughout the trial, but the fastest rate of loss happened in the middle months, typically months three through seven, once the dose had fully escalated and appetite suppression was well established