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These typically improve with time
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Effect of bariatric surgery on oncologic outcomes: a systematic review and meta-analysis

The Phase 2 data shows weight loss approaching what previously required bariatric surgery, plus meaningful drops in hemoglobin A1C, blood pressure, triglycerides, and liver fat

That would be a recipe for intense side effects

(2019), adults with elevated blood sugar levels taking 200mg of Eriomin per day saw a significant improvement of 15.6% in GLP-1 levels by week 12, compared to a 0.2% increase in the placebo group
