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Using an integrated ligand and structure-based virtual screening pipeline, explicitly combining complementary ligand-based descriptors, multi-fingerprint similarity, electrostatic similarity, pharmacophore modeling, and multi-conformation docking under a consensus-driven selection strategy, we were able to identify three chemically distinct classes of GLP-1R agonist candidates: GQB47810, a non-peptidic molecule

Increases GLP-1 naturally* *Based on preclinical studies Formulated with: Akkermansia muciniphila generates the postbiotics propionate and p9 which induce GLP-1 production

0.6 mM), and cell viability was detected using the cell counting kit-8 (CCK-8) assay

But thus far, the data dont show this.