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These recommendations are very consistent with the key points from the most current international guidelines, especially those published, in 2024 and 2025, by multi-society groups in both the US and the UK 1-3

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This may include people who: Are early in treatment Recently changed their dose Already have nausea, vomiting, reflux, diarrhea, or constipation Have trouble staying hydrated Have diabetes or take blood sugar-lowering medication Have a history of pancreatitis Have gallbladder disease or gallstones Have liver disease or abnormal liver enzymes Drink heavily or binge drink Have a history of alcohol use disorder Are pregnant, trying to become pregnant, or breastfeeding Are taking other medications that interact with alcohol If any of these apply to you, do not guess