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Some patients report an immediate, sharp pins-and-needles sensation traveling along the vein, though this varies by individual sensitivity

some patients achieve greater loss while others see modest reductions

For NHS prescribing, adults are typically eligible for semaglutide if they have a BMI of 35 kg/m or above , or a BMI of 30-34.9 kg/m with at least one weight-related comorbidity such as type 2 diabetes, hypertension, dyslipidaemia, obstructive sleep apnoea, or cardiovascular disease

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The researchers didnt dive into this question in their research, but experts have some theories
