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Su composicin rene extractos vegetales estandarizados algunos bajo patente y respaldados por estudios cientficos, fibras solubles, protenas vegetales y el mineral cromo, actuando sobre cuatro ejes fisiolgicos complementarios: el metabolismo de las grasas, la sensacin de saciedad, el mantenimiento de la masa muscular y el equilibrio de la glucemia

About 40-50,000 patients receive GLP-1 receptor agonists or sodium-glucose cotransporter-2 inhibitors(SGLT-2i) drugs, 84,000 were treated with dipeptidyl peptidase-4 (DPP-4) and more than 200,000 received sulfonylureas, with tracking of major adverse outcomes of all-cause mortality, heart attack, stroke, need for coronary revascularization

The data indicates that approximately 60% of the lost weight is regained within a year of discontinuing the drug

The drug is indicated for chronic weight management in patients with a body mass index (BMI) of 27 kg/m2 or greater who have at least one weight-related ailment or in patients with a BMI of 30 kg/m2 or greater

doi:10.1038/modpathol.2014.113 He L, Zhang S, Zhang X, Liu R, Guan H, Zhang H