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IPTW resulted stable throughout the follow-up period

Historically, the liver has been acknowledged as the main location where metformin reduces glucose levels, however, there is increasing evidence suggesting that the gastrointestinal tract also plays a significant role in its action

Semaglutide (Ozempic, Wegovy, Rybelsus) Strengths: Strong evidence base with extensive clinical trial data Once-weekly dosing (injection) or daily (oral) Excellent glucose control and weight loss Proven cardiovascular and kidney benefits Widely available Considerations: Gastrointestinal side effects common initially Cost without insurance is significant Best for: Most patients seeking strong glucose control with weight loss

However, the adage that there is no such thing as a free lunch remains true

We are currently monitoring for these to occur in the Ozempic MDL