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Aten Primaria (2017) 49:2949

In isolated murine -cells, GLP-1 stimulates exocytosis of the insulin granules and this can be blocked by co-treatment of GLP-1 with the adenylate cyclase inhibitor MDL 12330A [508]

GP References 1

A recent Survey of Ophthalmology review synthesized findings from cardiovascular outcomes trials, retrospective database analyses, meta-analyses and preclinical studies involving semaglutide, liraglutide, dulaglutide and related agents across six ocular conditions: diabetic retinopathy (DR), glaucoma, nonarteritic anterior ischemic optic neuropathy (NAION), age-related macular degeneration (AMD), idiopathic intracranial hypertension (IIH) and dry eye disease (DED)

These data suggest that activation of the HPA axis antagonizes the satiation effect of GLP-1R agonism [819]