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When used with insulin or sulfonylureas, these medications may increase hypoglycemia risk, requiring dose adjustments of those agents

Previous studies have shown people with a BMI 40, also known as class 3 obesity, and women have an increased risk of thyroid cancer

GIP may reduce oxidative stress in endothelial cells and visceral adipose tissue and decrease the secretion of inflammatory cytokines [36]

doi: 10.3389/fendo.2021.609110
1 T2DM remains as one of the leading causes of disability and death worldwide mainly due to its long-term vascular complications