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( 3 ) In the SURMOUNT-4 trial, patients with obesity receiving tirzepatide had a mean 25.3% body weight loss over 88 weeks

This loss of lean mass can potentially lower your basal metabolic rate (BMR), the rate at which your body uses energy when at rest
Semaglutide works best when you inject at roughly the same time each week

Gastric emptying was measured using paracetamol as a marker and emptying rates were seen to be lower in the GLP-1 group (4)
