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This reduces the risk of diabetic ketoacidosis, and you should contact your healthcare team for guidance on when to restart treatment

Pain or Tenderness: Pain often starts in the calf, feeling like cramping or soreness, and may extend to the foot or thigh

As patients lose weight, they often report: Improved mobility and reduced joint discomfort Better sleep quality and reduced sleep apnoea symptoms Improved exercise tolerance Improved mood and psychological wellbeing Some patients may experience reduced inflammatory markers (such as C-reactive protein) as metabolic health improves

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Spending on shareholder enrichment appears to take priority over research and development (R&D), with Novo Nordisk spending 41% more on dividends and buybacks than on R&D over the past five years