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Without testosterone replacement, GLP-1 medications alone may cause 15-40% of weight loss to come from lean mass rather than fat

The real key is going to be side effects over time, if retatrutide is like other drugs in the class then the side effects should decrease with time, but unfortunately, we dont have that today, at this point I have some questions and minor concerns but without the data over time its hard to speculate about tolerability further beyond saying its similar to other drugs in the class

There are no documented contraindications between GLP-1 medications and home RF, microcurrent, or LED therapy

doi: 10.1056/NEJMoa2309000

Novo and Lilly have asked the FDA to bar compounders from using their active ingredients and filed lawsuits against compounders and related manufacturers