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As many of their effects influence weight loss and management, the variety of formulations provide tailored treatment options for many individuals

While GLP-1s clearly are effective for weight loss, experts may be concerned if their patients do not make other lifestyle changes, for example, changing their diet or being more active

The 52-week randomized, open-label trial enrolled a total of 504 patients with a mean baseline A1C of 8.3%
A standard 16-week protocol following the 2mg, 4mg, 8mg, 12mg escalation requires approximately 104mg total

Furthermore, DPP4 expression in adipose tissue is increased in obese compared to lean individuals in both subcutaneous and visceral adipose tissue (4, 5)