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As many of their effects influence weight loss and management, the variety of formulations provide tailored treatment options for many individuals

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While GLP-1s clearly are effective for weight loss, experts may be concerned if their patients do not make other lifestyle changes, for example, changing their diet or being more active

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The 52-week randomized, open-label trial enrolled a total of 504 patients with a mean baseline A1C of 8.3%

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A standard 16-week protocol following the 2mg, 4mg, 8mg, 12mg escalation requires approximately 104mg total

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Furthermore, DPP4 expression in adipose tissue is increased in obese compared to lean individuals in both subcutaneous and visceral adipose tissue (4, 5)

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