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While it is unclear if this risk applies to humans, patients with a history of thyroid cancer or multiple endocrine neoplasia syndrome type 2 should avoid using semaglutide

This is the intended therapeutic effect, but it can feel unusual initially

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Overall, the proteomic data indicated that semaglutide effectively mitigated hepatic lipid deposition and key pathways related to fatty acid/lipid protein signalling and fibroblast proliferation ( Figure S11 ), further supporting our histological and single-cell RNA sequencing findings

Therefore, this study was exempt from federal regulations covering human subject research and did not require institutional review board review