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The proportion of patients with PCOS who were prescribed semaglutide or tirzepatide increased more than 7-fold over the study period

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

Together with glucagon (GCG) , they form an integrated hormonal network that maintains glucose and energy balance

The same group showed that GLP-1 continued to suppress lipogenesis and increase lipolysis in day 14 differentiated cells from subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT), with the effects being more pronounced in SAT [31]

The researchers said they don't know whether the effects will persist when people have been taking the drugs for many years, or whether the brain will adapt and the GLP-1 effects will weaken