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GLP-1 agonists may: Optimize high-risk patients before surgery Improve metabolic control Potentially reduce surgical risk But durable long-term outcomes in severe obesity still rely heavily on: Surgical intervention Lifelong follow-up Nutritional monitoring Multidisciplinary care The future may not be medicine vs surgery. It may be the intelligent integration of both
Among the numerous metabolic effects of GLP-1 are the glucose-dependent stimulation of insulin secretion, decrease of gastric emptying, inhibition of ...

Patents are falling across China, Brazil, Canada, and Turkey this year representing ~40% of the world's population

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While not statistically significant, GLP-1 RAs also exhibited a trend towards fewer myocardial infarctions (HR 0.83) and lower mortality rates (HR 0.83) than SGLT2 inhibitors
