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Monthly body fat composition is done to monitor patients progress

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Semaglutide can attenuate inflammation in MASLD by downregulating the IRE1-XBP1-C/EBP (inositol-requiring transmembrane kinase/endonuclease-1-X-box binding protein 1-CCAAT/enhancer binding protein ) pathway in macrophages ( 2 ( 4.1.2 GLP-1RAs regulate the immune cells to protect the liver against fibrosis and neoplasia Exenatide and liraglutide can elevate cAMP levels and reduce the M1/M2 ratio through the cAMP-PKA-STAT3 pathway, resulting in amelioration of injured liver function and liver inflammation (Somm et al., 2021)

Stabilization strategies should therefore focus on maintaining proportionality between oxidative throughput and the substrate pools that support (i) redox currency, (ii) antioxidantanabolic coupling, (iii) cofactor-dependent enzymatic velocity, and (iv) bile aciddependent absorption (Sect