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Similarly, in patients with NAFLD, DPP4 activity in serum correlates with markers of liver damage, such as serum gamma-glutamyltranspeptidase and ALT levels, but do not correlate with fasting blood glucose levels and HbA1c values (156, 157)

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T., Wang, J., Wu, H

It had a differentiated safety profile with no nausea-like symptoms in preclinical lab studies

The CVOT of oral semaglutide in people with type 2 diabetes and established CVD, chronic kidney disease (CKD) or both demonstrated a significant reduction in MACE compared with placebo (McGuire et al, 2025)