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[DOI] [PubMed] [Google Scholar] 10.Chiasson J.L., Josse R.G., Gomis R., Hanefeld M., Karasik A., Laakso M., STOP-NIDDM Trial Research Group Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: The STOP-NIDDM trial

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In some supervised clinical contexts, yes

Inhibition of Epac activity using ESI-09 significantly attenuated the protective effects of exendin-4 on MG-induced oxidative stress, apoptosis, and mitochondrial dysfunctions ( Figure 3 )