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In a pivotal phase 2 randomized trial published in the New England Journal of Medicine, orforglipron, a once-daily oral nonpeptide GLP-1RAs, demonstrated substantial and sustained weight loss among adults with obesity, with efficacy comparable to injectable agents and an acceptable safety profile [35]

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The risk of developing IIH increases significantly with increasing body mass index (BMI), or following recent weight gain (3) and can go into remission with weight loss (5)

Understanding the interplay between caffeine and Wegovy can empower users to optimise their experience while minimising discomfort

Weight loss drugs like retatrutide, semaglutide, or tirzepatide can accelerate results but carry risks such as increased heart rate or muscle loss, according to Dr
