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Patients and clinicians should nonetheless remain alert to this possibility, particularly given the substantial weight loss retatrutide has produced in phase 2 trial settings (see the New England Journal of Medicine , 2023)

Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: A randomized trial
ROCKWOOL Foundation Research Unit, Copenhagen, Denmark

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Others find that even mild spice triggers discomfort
