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Key Considerations for Patients on Weight Loss Medications (Mounjaro/Wegovy) Before Surgery Many patients are using GLP-1 medications such as Semaglutide (Wegovy) or Tirzepatide (Mounjaro) to support weight loss

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Abbreviations BAT: Brown adipose tissue CEX: C-terminal extension CNS: Central nervous system DIO: Diet-induced obese DPP-IV: Dipeptidylpeptidase-IV EMA: European Medicines Agency FDA: Food and Drug Administration GcgR: Glucagon receptor GIP: Glucose-dependent insulinotropic polypeptide GIPR: GIP receptor GLP-1: Glucagon-like peptide 1 GLP-1R: GLP-1 receptor OXM: Oxyntomodulin PEG: Polyethylene glycol STZ: Streptozotocin T 3 : Thyroid hormone References Obesity and overweight fact sheet

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Treatment and mechanism of fecal microbiota transplantation in mice with experimentally induced ulcerative colitis