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(Conference summary of real-world data on GLP-1RA + progestin regimens.) Consultant360 Hsieh TYJ, et al
AMPK antagonizes mammalian target of rapamycin (mTOR) activity, and its downstream effector, p27, inhibits cyclin-dependent kinase 2 (CDK2), thereby blocking the G1/S transition in the cell cycle, halting cell division, and subsequently inhibiting cellular proliferation [57]
[DOI] [PubMed] [Google Scholar] 16.Hellerstrom C., Hellman B., Petersson B., Alm G
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