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It was a limitation of the current study that only single-dose pharmacokinetics were directly measured

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Little enhancement of meal-induced glucagon-like peptide 1 secretion in Japanese: Comparison of type 2 diabetes patients and healthy controls

Although it is a single molecule, tirzepatide pharmacologically activates two metabolic receptors, GIP and GLP-1, which have both overlapping and nonoverlapping expression and function, the researchers wrote in NEJM