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Description
The SURPASS-3 study was set up to investigate the efficacy and safety of tirzepatide versus a titration of the basal insulin degludec inadequately controlled by an oral therapy of T2D by metformin with or without an SGLT2 inhibitor comedication for 52 weeks (72)

PMCID: PMC10341852

Novo Nordisk, while also strong, was until recently more focused on diabetes

Pain Pain GLP-1s are also being investigated for osteoarthritis pain and disease progression

"Treatment not working" is not listed as a refund basis