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After losing well over 100 pounds with the aid of GLP-1 medications, the state of Massachusetts wants to take away what is a lifetime drug and condemn me back to immobility and isolation, Sharp said in a statement circulated by the Massachusetts Teachers Association

Let's explore the research and real-world data on the durability of weight loss achieved with GLP-1 analogue therapies and the vital role of lifestyle changes in maintaining results over time

Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms

Many researchers find that injection timing affects the severity of GI side effects

Accessed March 13, 2026