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Description
Liraglutide depolarizes membrane potential and increases the spontaneous action potentials directly through postsynaptic GLP-1R in the ARC neurons expressing POMC (Secher et al., 2014

For weight management, higher doses such as 8 mg and 12 mg once weekly delivered the most dramatic results

DDP-4: dipeptidyl peptidase 4

It is therefore not clear how much of the placebo effect resulted in the drug treatment outcome

Cardiovascular risk reduction : Reduces the risk of cardiovascular events in patients with type 2 diabetes and established cardiovascular disease
