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However, they may become more important as weight stabilizes and patients facial appearance improves with treatment

Among the differentially expressed genes, 58 modules were identified as closely associated with microglial GLP-1R pathways and features of nerve injury, including pain hypersensitivity, ligation, paw withdrawal latency, and anxiety-related behaviors [64]

There are also GLP-1 tablet alternatives like the Wegovy tablet available if you would find it more suitable to take an oral pill rather than injecting

Short-term use of loperamide may be appropriate for acute episodes, but this should only be done under medical supervision and avoided if you have blood in your stool, fever, or suspected infection

Another systematic review [80] examined the effect of GLP-1RAs on psychiatric symptoms, with studies classifying primary or secondary psychiatric outcomes