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Sources: SURMOUNT-1 (NEJM 2022), STEP-1 (NEJM 2021)
This REDEFINE 4 clinical trial spent 84 weeks comparing the effectiveness of CagriSema versus tirzepatide (Zepbound) in 809 people with obesity
When Rice May Cause Nausea or Digestive Discomfort Some semaglutide users experience mild nausea, constipation, or bloatingside effects that become more pronounced when eating high-volume meals or foods that slow digestion further
Reported time-to-onset analysis A total valid case of 52 was used for TTO analysis (Fig
The safety trade-off is real but manageable
