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doi: 10.1111/mmi.12859
Glycemic Safety Of particular importance given the glucagon receptor agonism component of retatrutide, there were no clinically significant increases in blood glucose or concerning hyperglycemic events despite glucagon's classical glucose-raising effects - confirming that the GLP-1 component successfully counteracts glucagon's impact on glucose homeostasis
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The short answer: We don't know
In other cases, higher doses are more appropriate
Srivastava, G
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