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In addition to reduction in A1C and body weight, the semaglutide 2.0 mg arm of the trial saw a greater proportion of patients achieve an A1C less than 7% (67.6% vs 57.5% [OR, 1.60

While these agents show great therapeutic efficacy in improving body weight and glycemic control, their use in developing organisms raises concerns about pleiotropic effects and impairment in developmental plasticity, requiring integrative approaches and cautious evaluation