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Sitagliptin protects renal ischemia reperfusion induced renal damage in diabetes

The energy balance defect that causes obesity and visceral adiposity is serious and predisposes individuals to complications, such as atherosclerosis, hepatic steatosis and type 2 diabetes [1]

GLP-1 medications are unsuitable for individuals with: A personal or family history of medullary thyroid carcinoma Multiple endocrine neoplasia type 2 (MEN 2) They should also be used with caution in patients with severe gastrointestinal disease

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The goal should be improved metabolic function, better body composition, and a lower-risk physiologic state