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To improve the health of Americans, in June 2021, the FDA approved semaglutide, a once-weekly injection, for chronic weight management in adults when used in combination with a healthy diet and exercise.

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Further, trimetazidines demonstrated safety and tolerability provide a strong rationale for clinical trials to test its efficacy to treat bipolar depression that could fast-track its repurposing to address such an unmet need as bipolar depression.

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